The Association Between Antihypertensive Medication Nonadherence and Visit-to-Visit Variability of Blood Pressure

نویسندگان

  • Ian M. Kronish
  • Suzanne Oparil
  • Barry R. Davis
  • Lara M. Simpson
  • Marie Krousel - Wood
  • William C. Cushman
  • Tara I. Chang
  • Paul Muntner
چکیده

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Association between antihypertensive medication adherence and visit-to-visit variability of blood pressure.

It has been hypothesized that high visit-to-visit variability (VVV) of systolic blood pressure (SBP) may be the result of poor antihypertensive medication adherence. The authors studied this association using data from 1391 individuals taking antihypertensive medication selected from a large managed care organization. The 8-item Morisky Medication Adherence Scale, administered during 3 annual s...

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BACKGROUND Medication nonadherence is widespread, but there are few efficient means of detecting medication nonadherence at the point of care. Visit-to-visit variability in clinical biomarkers has shown inconsistent efficiency to predict medication adherence. OBJECTIVE To examine the performance of visit-to-visit variability (VVV) of hemoglobin A1c to predict nonadherence to antidiabetic medi...

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Visit-to-visit variability of blood pressure: current knowledge and future research directions.

Blood pressure (BP) is known to vary over time within individuals. Although variability between office visits has traditionally been regarded as a barrier to the accurate measurement of BP, several recent studies have reported strong associations between visit-to-visit variability (VVV) of BP and increased risk for cardiovascular outcomes. In this article, we review data on VVV of BP and outcom...

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Nonadherence to antihypertensive drugs is associated with adverse outcomes; however, mediators of this relationship are poorly understood. We examined the association between the International Classification of Diseases-Ninth Revision code for medical treatment nonadherence (V15.81) assigned before initiation of antihypertensive drug therapy and all-cause mortality in a large cohort of incident...

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Visit-to-visit blood pressure variability and carotid artery atherosclerosis: heart rate was not a confounder.

Visit-to-Visit Blood Pressure Variability and Carotid Artery Atherosclerosis: Heart Rate Was Not a Confounder To the Editor: We read the interesting recent article by Muntner et al,1 who found that increased visit-to-visit systolic blood pressure (SBP) variability was a significant predictor for all-cause mortality independently of age, sex, and average SBP. On the other hand, in the Letter to ...

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تاریخ انتشار 2016